ESPN3 Preview Show Caps Southland Social Media Day

first_imgHOUSTON — ESPN3 will stream the 2018-19 Southland basketball preview show Wednesday at 6 p.m. CDT, capping Southland Basketball Social Media Day at the Toyota Center. All 26 women’s and men’s head coaches are scheduled to attend, with the event running from 9 a.m.-2:30 p.m. CDT. Both the men and women begin their seasons on Nov. 6, while conference action first tips on Dec. 28. Basketball Media Event LineupWednesday, Oct. 10 – Toyota Center, Houston(All times Central) In addition to the initial Oct. 10 airing at 6 p.m. on ESPN3., archived video of each coach’s comments and select quotes from each attendee will be available after the conclusion of the event. Fans are encouraged to follow conference and team social media platforms throughout the day. Activities include: Media availability for each coach, including time for one-on-one interviews. ESPN broadcasters Carley McCord and Lincoln Rose sitting down for Q&As with each coach in the Houston Rockets’ visitors’ locker room. The ESPN3 preview show, available via ESPN.com/watch and ESPN apps, will be archived immediately following its initial airing. All 26 coaches participating in social media activities, which fans can follow on the @SouthlandSports Facebook, Twitter and Instagram accounts. They’ll take part in a friendly shooting competition, which Emily Honeycutt will host on the conference’s Instagram Story. Each team’s account will also provide an in-depth look at their coaches’ participation. Deputy Commissioner John Williams, former men’s basketball head coach at Purdue Fort Wayne, will visit with each coach for segments that will run throughout the preseason on the Southland YouTube channel.The day will begin with comments from Southland Conference Commissioner Tom Burnett, now in his second year as a member of the NCAA Division I Men’s Basketball Committee. Results of the predicted order of finish polling for the conference will be unveiled at 9 a.m. 9:00 – Opening remarks – Southland Commissioner Tom Burnett9:15 – Stephen F. Austin9:40 – Abilene Christian10:05 – Northwestern State10:30 – Southeastern Louisiana10:55 – Nicholls11:20 – New Orleans11:45 – Texas A&M-Corpus Christi12:10 – Central Arkansas12:35 – Houston Baptist1:00 – Sam Houston State1:25 – Lamar1:50 – McNeese            2:15 – Incarnate WordMedia are encouraged to attend the event in person, which will include participation from all 26 Southland head basketball coaches — 13 women’s and 13 men’s. Attendees should enter the Toyota Center at the Administrative entrance near the intersection of Clay Street and La Branch Street. No RSVP is necessary for media.last_img read more

Read More →

Easy and inexpensive test could one day help guide epilepsy treatment

first_imgThe test is a two-step process. First, HLA alleles are identified and amplified using LAMP. They are then exposed to an interdigitated electrode (IDE) sensor embedded with DNA probes for HLA-B*15:02. If the amplified alleles hybridize with the probes, the electrical impedance of the sensor surface changes, identifying the alleles as HLA-B*15:02.”The isothermal amplification and electrical-based detection were chosen in order for [the method] to be amenable for miniaturization into a device that can be used at the point of care,” said Soraya, a faculty member at Hasanuddin University, Indonesia.The study involved a proof-of-concept phase to establish a protocol. Then, the protocol was evaluated for sensitivity and specificity using a sequence of crude blood samples for which the allele type was already known.The evaluation resulted in one false negative and two false positives, which translates to 92.9% sensitivity and 84.6% specificity.The false-positive samples differed by only two base pairs (HLA-B*13:01). The HLA-B*13:01 allele also is common in Asian populations but does not appear to confer risk for carbamazepine-induced SJS/TEN. “This must be addressed in future studies,” said Soraya. Subsequent studies also will use larger sample sizes and test more diverse HLA genotypes across various ethnic populations.Ultimately, she said, “The technology can be customized to detect other alleles relevant in pharmacogenetics testing. It’s also applicable to other gene diagnostics, including pathogen detection.”Source: https://www.ilae.org/ Reviewed by Alina Shrourou, B.Sc. (Editor)Sep 4 2018An easy and inexpensive test for the HLA-B*15:02 allele could one day allow clinicians to quickly identify which epilepsy patients are at risk of carbamazepine hypersensitivity, according to study results presented by Gita V. Soraya at ILAE’s 2018 Asian & Oceanian Epilepsy Congress in Bali.”This study has provided the proof of principle evidence for the development of a handheld device that can be used at the clinic or bedside for rapid detection of the HLA-B*15:02 allele,” said senior author Patrick Kwan, chair of neurology at the University of Melbourne, Australia. “This method will avoid the current delay and reduce the cost of testing and make it accessible to patients living in remote areas, allowing carbamazepine to be prescribed more safely.”Widely used globally as a first-line treatment for epilepsy, carbamazepine also is prescribed for other conditions, such as bipolar disorder and neuralgia.Carriers of HLA-B*15:02 who take carbamazepine are at high risk for Stevens-Johnson Syndrome or toxic epidermal necrolysis (SJS/TEN). These skin reactions can have an unpredictable course and carry mortality rates of up to 30%.The allele was first identified in Han Chinese but has since been found in many other Asian populations, including those in Thailand, Malaysia and Hong Kong. The frequency appears lower in India -; about 2% to 4% -; and is rare in Japan, Korea, and individuals not of Asian descent.Regulatory agencies, including the U.S. Food and Drug Administration, recommend HLA-B*15:02 screening in patients with Asian ancestry before prescribing. However, because HLA screening is not feasible in most low-resource Asian countries, clinicians avoid prescribing carbamazepine altogether. As a result, patients that could have done well on the drug may receive less effective or more expensive medications.Soraya noted that the new test has several advantages:Related StoriesAn active brain and body associated with reduced risk of dementiaHow cell-free DNA can be targeted to prevent spread of tumorsHIV DNA persists in spinal fluid despite treatment, linked to cognitive impairment It uses crude blood samples (no DNA purification needed). It requires less blood. The IDE format requires no labeling or staining of DNA. Turnaround time is about 80 minutes. Testing can be completed at the point of care.last_img read more

Read More →